In cervical carcinoma the virus is integrated into the host cell chromosomes, this leads to further deregulation of E6/E7 expression. CIN: Cervical intraepithelial neoplasia. Reproduced with ...
[36] Detection of E6/E7 mRNA was strongly correlated with severity of the lesion; more than 90% of CIN 3 cases and all ... a sufficient cause of cervical carcinoma, and the first step in ...
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