According to the American Cancer Society, survivors of childhood cancer can face health problems later in their adult life.

Researchers have developed CRISPR-sciATAC, a novel integrative genetic screening platform that jointly captures CRISPR gene perturbations and single-cell chromatin accessibility genome-wide.

In a study recently published in Nature Genetics, researchers from Nano Life Science Institute (WPI-NanoLSI), Kanazawa University explore chromatin accessibility, i.e., endogenous access pathways ...

Chinese researchers have developed a technology that sheds light on how the three-dimensional (3D) organization of plant ...

In situ chromatin states can be identified based on how accessible the DNA is to nucleases. The DNA in heterochromatin is inaccessible to outside proteins, including exogenous nucleases ...

A newly identified rare cell subset that drives immune tolerance in dietary and gut microbiota may offer a new therapeutic ...

The open chromatin landscape can act as a cell type specific filter to define the accessibility of the genetic blueprint to the transcriptional machinery. Currently, little is known about the 5-HT ...

These modifications increase chromatin accessibility, influencing growth, differentiation, and ion transport, with contrasting effects on normal and colorectal cancer cells. Study: Short-chain ...

Figure 1. Experiments on cell lines confirm that cfDNA TSS coverage is negatively correlated with chromatin accessibility and RNA transcription levels in cells. This study is led by Dr. Xun Lan ...

ArchR can be used to analyze single-cell data on chromatin accessibility—it shows the ways that DNA can be involved with transcription. More specifically, it can be used to analyze single-cell ...