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Specific host factors, such as immune cell activity, sex hormones and microbiota composition, influence the ability of Staphylococcus aureus bacteria to colonize the gut of mice.
One of its key toxins, α-toxin, compromises epithelial barriers by activating the metalloproteinase ADAM10, which disrupts cell junctions. 1 To adhere to host tissues, S. aureus uses surface ...