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Cell Line Development Process – Challenges and Best PracticesCell line development plays a pivotal role in the manufacturing of therapeutic proteins, vaccines and other biologics.
Someday researchers may create new ES cells lines using a technique similar to that brought to bear in the birth of Dolly, the famous cloned sheep. Finally, there was the question, still somewhat ...
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Complex engineering of human cell lines reveals genome's unexpected resilience to structural changesThe most complex engineering of human cell lines ever has been achieved by scientists, revealing that our genomes are more resilient to significant structural changes than was previously thought.
Gene-editing tools such as CRISPR/Cas9 can be used to create isogenic cell lines, which can be further used to model a specific patient population. An isogenic cell line was created to model ...
During that time, explained Seil Jang, antibody engineering team lead at Y-Biologics, the drawbacks of the mutation-based engineering system typically used to create bispecific antibodies became ...
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