The interplay between aging and cellular senescence reveals insights into chronic inflammation and potential strategies for enhancing healthspan and longevity.

Despite its prevalence, the exact mechanisms driving MASLD remain unclear, limiting the development of effective treatments.

Australian researchers have identified a surprising mechanism focusing on telomeres -- protective caps at the ends of chromosomes -- that can help cells defend against cancer.

Figure 2: Nocodazole-mediated cell cycle arrest of adherent HeLa cells, as measured using a laser-scanning microplate cytometer (Acumen e X3). Nuclear-ID Red DNA stain is a far-red–emitting dye ...

such as cell cycle arrest or programmed cell death. As a mass of cancerous cells grows, it can develop into a tumor. Cancer cells can also invade neighboring tissues and sometimes even break off ...

They do this to avoid cancer. "This can lead to cell cycle arrest, or death, to prevent these damaged cells with chromosome errors from dividing further. This suggests telomeres have another anti ...