From live-action to classic friendships, top productions like Disney and Nickelodeon have created female iconic cartoon duos with polarising personalities playing off one another with comedic timing.

There, they don’t even necessarily need to be human. These are the top duos from animation. To make the list, they have to be fundamentally considered a duo. For example, Homer and Marge are ...

This list contains only the best cartoon duos, actor duos from movies or TV shows, and celebrity and music duos. Renowned film critic Cideshow explained the significance a duo could have.