On Crowncast, Enrico Pesenti explains how cancer drug resistance forms and how advanced technologies are helping researchers ...

Glioblastoma is a type of brain cancer ... includes the drug temozolomide (TMZ). In many cases, TMZ kills glioblastoma cells, but a significant portion of patients show resistance to the drug.

Cancer patients invariably develop resistance to targeted drugs, so drugmakers develop strategies to combat it before ...

Proteins play a central role in virtually every disease. They are the building blocks of life, serving as essential ...

A team of University of Kentucky Markey Cancer Center researchers has found the mechanism that grants prostate cancer resistance to enzalutamide, a frequently used drug. The article is published ...

Recent research sheds light on how changes in the chemical structure of a protein called Interleukin-6 affect lung cancer’s ...

Castration resistance can happen for many reasons ... oncologists (medical doctors who diagnose and treat cancer) may try a ...

Galmed Pharmaceuticals (Nasdaq: GLMD) enters into a Sponsored Project Agreement with Virginia Commonwealth University (VCU) to evaluate Aramchol's effect on overcoming drug resistance in ...

A new drug is showing promise in tackling treatment-resistant ovarian cancer. Relacorilant, the drug tested in a phase 3 ROSELLA trial with Corcept Therapeutics in California, was found to improve ...

Acquired resistance to doxorubicin significantly reduces its therapeutic efficacy, limiting its clinical use in breast cancer treatment. Pan-AKR1C inhibitors have demonstrated potential in restoring ...

City of Hope researchers demonstrate proof of concept for a novel targeted therapy for pancreatic cancer, exploiting transcription-replication conflicts to combat treatment resistance.

Collaboration builds on breakthrough findings published in Nature Communications (link) linking lipid metabolism to cancer drug resistance, supporting Aramchol's novel mechanism as a promising ...