VPS72 has been identified as a key genetic player in liver cancer, highlighting its role in altering fat metabolism.

Liver cancer is a lethal disease with limited treatment options for advanced stages. While risk factors such as viral ...

Thus, the activation of mTORC1 by glutaminolysis during nutritional imbalance inhibits autophagy and induces apoptosis in cancer cells. Importantly, rapamycin treatment reactivates autophagy and ...

When an immune T cell divides into two daughter ... of its Bloomberg-Kimmel Institute for Cancer Immunotherapy. To determine the uneven distribution of mTORC1, the scientists activated mouse ...

Cancer cells need nutrients to survive and grow. One of the most important nutrient sensing molecules in a cell is called mTORC1. Often called a master regulator of cell growth, it allows cells to ...

Canadian scientists have identified a promising therapeutic target to attack to prevent breast cancer from recurring: the ...

mTORC1 regulates cellular metabolism by balancing the break down (catabolism) and build up (anabolism) of molecules within cells ... important implications for cancer research, suggesting that ...

Canadian scientists have identified a promising therapeutic target to attack to prevent breast cancer from recurring: the ...