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Researchers deciphered the structure of an ion channel from the rod cells of the eye (shown in blue) while it interacts with the protein calmodulin ... such as the heart. (Image: Dina Schuster ...
To learn that, the researchers had to coax bacterial cells to make human versions of sodium channel proteins and calmodulin, purify the protein complexes, and image them with a technique called X ...
This image shows the three-dimensional structure of death-associated protein kinase (green and yellow) when bound to calmodulin (violet and blue). It was obtained by X-ray crystallography.
The researchers were surprised to discover that a protein called calmodulin binds to the sodium channel, keeping it open by preventing the plug from forming. Calcium ions, in turn, regulate the ...
Wand and his colleague used nuclear magnetic resonance (NMR) relaxation imaging to track the activity of the calmodulin-peptide protein complex across a spectrum of 13 temperature settings that ...
We have found that in CaMKIV −/− mice—which are deficient in a component of the calcium–calmodulin-dependent protein kinase ... Pennsylvania). Images were obtained with an Olympus ...
We suggest that activation of the calmodulin protein protects against the development of pancreatitis. There is a strong correlation between alcohol intake and incidence of pancreatitis ...
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