and one that coexpressed CD4 and CD8. In contrast to the angioimmunoblastic T-cell lymphoma cases, CXCL13 expression by the T cells was observed in only two out of 20 peripheral T-cell lymphoma ...

Scientists have identified potential new biomarkers that could indicate how someone diagnosed with metastatic melanoma will respond to immunotherapy treatment. Scientists at the UCLA Jonsson ...

How CD4+ T cells respond to Chikungunya virus may trigger long-lasting joint pain, mimicking autoimmune disease long after ...

CD4+ T cells, or helper T cells, are one type of lymphocyte that helps coordinate the immune response against infection and disease. They interact and activate other cells in the immune system.

Single-cell transcriptome landscape of circulating CD4+ T cell populations in autoimmune diseases. Cell Genomics , 2024; 100473 DOI: 10.1016/j.xgen.2023.100473 Cite This Page : ...

Association between CD47 expression and clinicopathologic characteristics and survival outcomes in MIBC. SWOG S1314: A randomized phase II study of co-expression extrapolation (COXEN) with neoadjuvant ...

S3). Immunohistochemical analysis showed a dense lymphocytic infiltration of the lamina propria positive for T-cell receptor (TCR) α, CD3, CD4, and granzyme B but which did not express TRBC1 ...

"We wanted to understand which SARS-CoV-2 proteins are highly targeted by CD4+ T cells, a T cell type that helps the immune response to fight against infectious pathogens," says Dr. Federico Mele ...

Indolent CD4+ cytotoxic chimeric antigen receptor (CAR) T-cell lymphoma involving the small intestine was diagnosed in a patient who had previously received ciltacabtagene autoleucel (cilta-cel ...

Researchers at Winship Cancer Institute of Emory University have identified a novel type of immune cell, called the stem-like CD4 T cell, that plays a pivotal role in anti-tumor immunity.

Findings were published this week in New England Journal of Medicine. ICL is a condition marked by too few CD4+ T-cells and has limited therapeutic options. The clinical definition of ICL is a CD4 ...