Experiments in mice confirmed that these dendritic cells, which carry a receptor called CX3CR1, collect and process both circulating and intestinal antigens, inducing production of a type of CD8 T ...

Deleting CX3C chemokine receptor 1 (Cx3cr1) negatively affects intestinal barrier function and exacerbates steatohepatitis in a mouse model NASH, according to a study from Christian Trautwein's ...

The study (“CX3CR1 + Mononuclear Phagocytes Control Immunity to Intestinal Fungi”), published in Science, shows a strong connection between fungi, immunity, and intestinal inflammation and ...

they shared many of the features that make intestinal macrophages unique. Both had high expression of CX3CR1 and scavenger receptors, were avidly phagocytic and produced IL-10 and TNF ...

The anti-CX3CR1 antibody, currently in preclinical development, works by inhibiting CX3CR1, a receptor involved in immune cell migration to inflammatory sites. By accelerating its development ...