Our lab and others have shown that a four-subunit CDK8 module can reversibly associate with the 26-subunit Mediator complex. The CDK8 module is 600 kDa in size and consists of MED12, MED13, CDK8, and ...
More information: Jaroslaw Dulski et al, Global Presence and Penetrance of CSF1R -Related Disorder, Neurology Genetics (2024) ...
Research shows male microglia are more sensitive to disrupted CSF1R signaling, uncovering potential links to sex-based disparities in neurological disorders. Study: The microglial response to ...