suggesting that these experimental systems are useful for learning about the CFTR protein's properties. The cell systems and the new pig model may also be helpful in testing therapies designed to ...

This model predicts a depletion in the volume of ... Important advances have improved our understanding of the role of the CFTR protein in the progression of suppurative pulmonary failure in ...

When the Scripps Research team then used the program to model how existing CF drugs impacted the structures, they discovered that although the drugs impact the CFTR protein in different ways none ...

The cystic fibrosis transmembrane conductance regulator (CFTR) is a complex protein that helps maintain fluid balance in several organs. Mutations in the CFTR protein can lead to symptoms of ...

Rather than looking solely at the function of the CFTR protein, the study, published in Proceedings of the National Academy of Sciences (PNAS), examined how CFTR proteins are organized on the cell ...

Rather than looking solely at the function of the CFTR protein, the study examined how CFTR proteins are organized on the ...

He has zeroed in on cystic fibrosis (CF), where patients do not make enough of a protein called CFTR. His team discovered how to use ASOs to make more of an imperfect but still functional version ...

Doctors have identified five categories of cystic fibrosis transmembrane conductance regulator (CFTR) genes. A person who inherits one copy of a mutated gene from each biological parent develops ...

CF is caused by a defective and/or missing CFTR protein resulting from certain mutations in the CFTR gene. Children must inherit two defective CFTR genes one from each parent to have CF ...

suggesting that these experimental systems are useful for learning about the CFTR protein's properties. The cell systems and the new pig model may also be helpful in testing therapies designed to ...