The CFTR (cystic fibrosis transmembrane conductance regulator) gene has been extensively characterized for its pathologic variability. However, the study of its overall random variability ...

The cystic fibrosis transmembrane conductance regulator has been studied for years but the new efforts have yielded important insights. Scientists at St. Jude Children's Research Hospital and ...

Hunt, Columbia University, at the 16th ECFS Basic Science Conference Pre-Conference Meeting entitled “CFTR: new insights on structure and function and implications for modulation,” in Dubrovnik, ...

In California, after detection of one CFTR mutation, the blood sample is sent for CFTR-DNA sequencing to rule out presence of a second pathogenic mutation. California has screened over 4 million ...

Nonclassic forms of cystic fibrosis have been associated with mutations that reduce but do not eliminate the function of the CFTR protein ... Common Mutations and DNA-Sequence Analysis in Patients ...

Previously, circular segments of DNA, called plasmids, have been used to deliver functional CFTR genes to lung cells, and that method has been found to stabilize lung function in patients.

“SalioGen’s Gene Coding approach seeks to insert a large piece of healthy CFTR DNA at a precise location within the CFTR gene, which could enable the expression of a functional CFTR protein in ...

In California, after detection of one CFTR mutation, the blood sample is sent for CFTR-DNA sequencing to rule out presence of a second pathogenic mutation. California has screened over 4 million ...