Here we increase levels of the cyclin-dependent kinase inhibitor Cdkn1b (p27kip1) in adult mice through doxycycline-inducible expression and show this results in reduced cell proliferation in ...

He and his team believe the answer lies in targeting the adenosine receptor 2A (Adora2a) -- a G-protein-coupled adenosine receptor found in high levels in the brain, immune cells, and blood vessels.

Aurigene Oncology Ltd. has divulged compounds acting as dual antagonists of adenosine receptor A2A (ADORA2A) and programmed cell death 1 ligand 1 (CD274; PD-L1) reported to be useful for the treatment ...

Chronic activation of the receptor Adora2a on the endothelial cells that line this important barrier in our brain can let factors from the blood enter the brain and affect the function of our ...

Chronic activation of brain receptor Adora2a that line this important barrier in our brain can let factors from the blood enter the brain and affect the function of our neurons. Researchers have ...