BCL6 functions by directly binding to specific ... bound to the promoter and suppressed transcription of the cell cycle arrest gene CDKN1A. Through this mechanism, BCL6 may facilitate the ...

In humans, p21 is encoded by the CDKN1A gene on chromosome six ... that could be developed from our growing knowledge of p21. Functions of p21 in the cell cycle, apoptosis, and transcriptional ...