p21/CDKN1A is most likely not the only protein ... downregulates a plethora of cell cycle genes, contributes to cell cycle arrest and is a target for cancer therapy. Researchers working on p53 ...

Cyclin-dependent kinase inhibitor 1, also known as CDK-interacting protein 1, or more simply as p21, is a cell cycle inhibitor that promotes both CDK/cyclin inhibition as well as cell cycle arrest ...