CDKL5, one of the five members of the CDKL family of genes, is important for proper neurodevelopment and associated with ...

Marinus sells Ztalmy (ganaxolone), an oral drug designed to reduce seizures in people with CDKL5 deficiency disorder. This is caused by changes in the CDKL5 gene, which encodes a protein that ...

The recommendations in this guidance represent the view of NICE, arrived at after careful consideration of the evidence available. When exercising their judgement, health professionals are expected to ...

Ganaxolone (Ztalmy) is not normally available on the NHS for treating seizures caused by cyclin-dependent kinase-like 5 (CDKL5) deficiency disorder in people aged 2 years and over. Your doctor should ...