News

News Medical3y
Screening memory T cell frequency using an optimized, multiplex flow cytometry assay
CD45RA, CD45RO, CD27, CD62L and CD95 are among the five T cell surface markers included in the panel for phenotyping T naive | memory | effector cells. The iQue ® Human T Cell Memory Kit was ...
Nature23y
Flow cytometric assessment of lymphocyte subsets, lymphoid progenitors, and hematopoietic stem cells in allogeneic stem cell grafts
During this process antigen-stimulated naive CD4 + T cells characterized as CD45RA + CD45RO − convert via ... each type of allografts by three-color flow cytometry analysis.
The New England Journal of Medicine19y
Effector Memory T Cells, Early Metastasis, and Survival in Colorectal Cancer
The local immune response within the tumor was studied by flow cytometry (39 tumors ... had increased numbers of CD8+ T cells, ranging from early memory (CD45RO+CCR7–CD28+CD27+) to effector ...
Nature11y
Chimeric antigen receptor-redirected CD45RA-negative T cells have potent antileukemia and pathogen memory response without graft-versus-host activity
Cell phenotypes were analyzed by flow cytometry. The following antibody clones were used: anti-CD3 (SK7, UCHT1), anti-CD56 (MY31, N901), anti-CD14 (MphiP9), anti-CD45RA (L48), anti-CD45RO (UCHL1 ...
The New England Journal of Medicine23y
Treatment of Chronic Plaque Psoriasis by Selective Targeting of Memory Effector T Lymphocytes
Flow-cytometric analyses were performed at each study visit to quantify populations of CD4+, CD8+, CD45RO+, and CD45RA+ T lymphocytes; CD19+ B cells; and CD16+ or CD56+ natural killer cells.