CCL2 orchestrates tumor-associated macrophage recruitment and osteoclastic differentiation, fostering tumorigenesis and skeletal metastases. CNTO 888 is a human IgG1κ monoclonal antibody with high ...

A randomized, double-blind study comparing corticorelin acetate with dexamethasone in patients with primary malignant glioma who require increased dexamethasone doses to control symptoms of ...

Morphine Does not Enhance CCL2 Production in Human Astrocytes and Microglial Cells To further assess if morphine's stimulatory effect on CCL2 production is specific to neurons or more generally ...

Stopping CCL2 inhibition paradoxically increases metastasis formation and leads to premature death thus thwarting the initially beneficial effects of the treatment. This has implications for the ...

The purpose of this study was to explore the influence of morphine on CCL2 expression by human neurons. Our focus was on CCL2 primarily because of accumulating evidence of the important role of ...