"B cells are important in the pathogenesis of asthma, and BTK inhibitors impact multiple important pathways including B-cell development, migration, and activation," explained Linda Rogers ...
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Some lymphomas become resistant to treatment. Gene discovery may offer path to overcome it.BTK inhibitors, including the commonly used drug ibrutinib, block B cells' signaling pathway. This is helpful for treating B-cell lymphomas because the cancers arise when this signaling pathway ...
BCL2 is an important regulatory protein in the apoptosis pathway, and its abnormal expression ... especially with the combination of BTK and BCL2 inhibitors, which has the potential to deliver ...
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