The current tuberculosis (TB) vaccine Mycobacterium bovis bacillus Calmette-Guérin (BCG) is the most widely used vaccine worldwide, but it does not prevent the establishment of latent TB or ...
The vaccine fell out of favor after the Lübeck disaster in 1930 in which 251 children received three doses of oral BCG that were contaminated with the pathogen Mycobacterium tuberculosis.
Bacillus of Calmette and Guerin (BCG) strain of Mycobacterium bovis live, attenuated culture preparation; 50mg per vial; pwd for intravesical administration after reconstitution and dilution ...
Engineered Mycobacterium bovis BCG encoding tetracycline-controlled phage lysin kill switches elicits protective immunity against subsequent M. tuberculosis infection in mice and non-human primates.