"We needed a version of BCG that triggers an immune response, but then you can flip a switch to eliminate the bacteria," said ...

The BCG vaccine was first used against TB in the ... had already tested a mix of different bacteria, coined "Coley's toxins," ...

However, because BCG is a biologic drug that uses benign bacteria, it is more complicated to manufacture than many other types of drugs. Serum Institute of India is the largest manufacturer of BCG ...

BCG provides efficient protection against TB ... post-exposure vaccines based on antigens that are expressed by the bacteria during latency, as recently discussed elsewhere 6.

The researchers genetically engineered the BCG vaccine so that it also produced this protein. The immune systems of the animals recognized it and were able to attack TB bacteria when the guinea ...

Best known for its role in tuberculosis prevention, the BCG vaccine is based on a harmless strain of bacteria related the one that causes tuberculosis. A generic drug with over 100 years of ...

Bacillus Calmette-Guérin (BCG) is a puny cousin of the bacteria that causes tuberculosis, and as such serves as an excellent vaccine against the disease. But BCG is also used to treat bladder cancer.

More than a dozen vaccines for tuberculosis are currently being tested in clinical trials. Some use whole bacteria as BCG does, while others deliver protein subunits or genetic material carried by ...

However, the BCG vaccine contains bacteria, unlike MMR shot that have viruses. Injecting the jab into the muscle allowed the bacteria to spread rapidly. Instead of protection against Measles ...

She explains that BCG acts as an antigen, teaching the body’s immune system to recognise and combat TB bacteria without causing infection. “BCG is a very important vaccine. An infant who is ...