A deal worth up to $712 million with the China-based biotech gives Cullinan T cell engagers aimed at BCMA and CD19, two ...

“This discovery was enabled by single-cell systems biology analysis of B cell development and integration with B-ALL drug sensitivity profiling and bulk RNA-sequencing data,” said co ...

A new study by researchers from Lund University in Sweden provides new insights into the origin and development of B cells in the body and in the gut, with implications for long-term immune health.

A cell nucleus is a busy place. Cellular proteins twist and pull DNA, folding the genome into intricate 3D structures that support functioning of its coding parts. This choreography is essential ...

New research from UT Southwestern suggests that RNA exosomes—the cellular machines that degrade old molecules of RNA—play a key role in the development of B cells, which are critical to the ...

Learn about B-Cell Acute Lymphoblastic Leukemia (B-ALL), its symptoms, diagnosis, causes, and treatment options. Understand ...

"Our study provides much-needed understanding of the phenotypes of B cells and plasma cells, which also play critical roles in early lung cancer development." Improved screening approaches have ...

“This ongoing process demands constant surveillance to eliminate autoreactive clones, which arise as errors in B cell development. Central and peripheral tolerance mechanisms prevent the ...

Details and references regarding individual diseases are provided in the Supplementary Appendix. CIDP denotes chronic inflammatory demyelinating polyneuropathy, Covid-19 coronavirus disease 2019 ...