scientists could only study autophagy by examining cells with electron microscopes. Using this tool, they established that after autophagosomes form, they fuse to the lysosomal membrane to form a ...

Although the double-membrane vesicles, now called autophagosomes ... thanks to improved electron-microscopy techniques and the use of fluorescently labelled proteins to monitor autophagosome ...

BORC-ARL8 is an essential regulatory factor in the fusion of lysosomes with autophagosomes and in ... Using cryo-electron microscopy (cryo-EM), the researchers discovered that the BORC complex ...

Using electron microscopy, the team was able to visualize the trapped proteins at a specific moment during the reaction and uncovered new ways the proteins coordinate their actions, which helps ...

The entorhinal cortex (EC) plays a pivotal role in memory function and spatial navigation, connecting the hippocampus with the neocortex. The EC integrates a wide range of cortical and subcortical ...