The findings were confirmed in mouse immunization studies involving model antigens as well as exposure to ... "We learned that there are two mechanisms: diversify and clone," Merkenschlager says.

For convenience, CloneMedia semisolid medium containing serum and cloning supplements is ... if accumulation of the fluorescent antigen around unfused B cells is an issue, one or both of the ...

The findings were confirmed in mouse immunization studies involving model antigens as well as exposure to ... “We learned that there are two mechanisms: diversify and clone,” Merkenschlager says.

A “complete eradication” of B cells with chimeric antigen receptor T-cell therapy is responsible for the long-term, drug-free remission from autoimmune diseases observed after treatment ...

Scientists create monoclonal antibodies by cloning a single antibody-producing cell line. In contrast to polyclonal antibodies, monoclonals are highly specific to an antigen. By fusing myeloma cells ...

Last November, results from the MITIGATE trial made headlines at ACR Convergence 2024 with positive phase 3 trial data for inebilizumab, an IgG1 monoclonal antibody targeting CD19, in patients with ...

monoclonal antibodies are derived from a single B cell clone and recognize only one epitope on an antigen. This unique specificity makes monoclonal antibodies powerful tools in research, diagnostics, ...