Epitope binning is an important step towards selecting the best monoclonal antibody for a specific therapeutic purpose as it allows researchers to narrow down the number of candidates by assessing ...

Not all antibodies that bind their intended target ... VHHs against the SARS-CoV-2 spike protein (S1). Using CAAD and epitope binning, multiple VHHs binding to different predicted epitopes on ...

and epitope binning. This equipment, based on biolayer interferometry (BLI) technology, offers quick results. Achieve more “hands-off” time and rise above the noise. This fluidics-free ...

Binds human Fc-fusion proteins and human IgGs. Suggested for kinetic screening, epitope binning, off-rate antibody ranking, and quick quantitation screening. High-performance nanobody-based ...

BLI can also be used to compare binding sites in binning assays to determine the region of a target protein to which an antibody binds. Epitope binning studies can increase the likelihood of ...

A technique invented by the lab, known as Electron Microscopy-Based Polyclonal Epitope Mapping (EMPEM), lets the researchers see exactly where on the HIV virus antibodies bind. When they carried ...

Epitope binning helps identify antibodies that block the same epitope on a target antigen and is crucial for identifying or engineering mAbs with favorable target recognition profiles. Octet's ...

Additionally, their AI platforms conduct epitope binning to screen hundreds of antibody sequences against functionally relevant epitopes, and can also evaluate their developability. The ...

Researchers identified that the dominant B cell epitope of Lachnospiraceae flagellins and the utilization of the flagellin ...

Malaria remains a significant global health challenge, causing over 600,000 deaths annually despite existing prevention and treatment measures. Current vaccines and monoclonal antibodies (mAbs) ...

A technique invented by the lab, known as Electron Microscopy-Based Polyclonal Epitope Mapping (EMPEM), lets the researchers see exactly where on the HIV virus antibodies bind. When they carried ...