Figure 1: Oncogene Her2/neu-initiated, Akt-mediated p21 Cip1/WAF1 inactivation as a suppressor of tumour growth and the cell cycle.
A groundbreaking study published in Research (2025, DOI: 10.34133/research.0545) has elucidated the molecular mechanisms by which protein phosphatase 2A (PP2A) regulates CD8+ T cell-mediated immune ...
Capivasertib (Truqap). This drug blocks some types of the AKT protein. It can be used if the cancer cells have changes in any of the AKT1, PIK3CA, or PTEN genes. Everolimus (Afinitor).
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