To overcome this obstacle, Atg7 was specifically inactivated in germ cells to explore the functions of autophagy in acrosome biogenesis. Interestingly, we found that Atg7-mutant male mice showed ...

Brazilian researchers have identified a previously unrecognized function of sperm that is unrelated ... reduced mitochondrial activity, decreased acrosome reaction, and cell death, thus affecting ...

suggesting that FER1L5 is critical for the acrosome reaction,” explains senior author Haruhiko Miyata. “Our results indicate that the function of ferlin proteins is well conserved from ...

These ensure that the organism functions as a whole. The head of the sperm contains the genetic material for fertilisation. The acrosome in the head contains enzymes so that the sperm can ...