Microtubule acetylation is essential for many cellular functions and has been linked to various health conditions, including cancer and brain disorders. Until this study, the molecular mechanism ...

McC analogs with an altered terminal amino acid retain the Trojan-horse mechanism of action but ... inside the producing cell is inactivated by acetylation catalyzed by the C-terminal domain ...

According to the research, this is an exceptionally subtle process in which PAX5 is sequentially stabilised and de-stabilized through a chemical modification known as acetylation. Two proteins are ...