the kinase inhibitor of interest is incubated with a target kinase, substrate, cofactors and radiolabeled ATP. During the kinase reaction, the radiolabeled phosphate is transferred onto the ...

Kinases are specialized enzymes that transfer phosphate groups from ATP to a substrate ... or serine/threonine (STK chip) residues within kinase substrates. Active kinases within a sample will ...

Researchers from the Icahn School of Medicine at Mount Sinai have introduced KiNet, an interactive web portal designed to ...

The reason for this lies in the cyclins' cooperation with a kinase. Kinases are responsible for phosphorylating amino acids in substrates—a key process for cell division. Another important ...