Figure 1: Structure of the AP2 adaptor core in complex with the dileucine peptide from CD4. Figure 2: Details of binding of the CD4 dileucine signal by the σ2 and α subunits of AP2. Figure 4 ...

Wan, C., Puscher, H., Ouyang, Y., Wu, J., Tian, Y., Li, S., Yin, Q., Shen, J. (2024) An AAGAB-to-CCDC32 handover mechanism controls the assembly of the AP2 adaptor ...

Our group focuses on two assembly pathways: adaptor protein assembly during vesicle budding and SNARE complex assembly during vesicle fusion ... We found that the assembly of AP2 is assisted by two ...