Findings suggested that the BB305 LVV vector was present in the AML blast cells, but there was not sufficient information to determine causality. Vector insertion in the AML cells from this ...

promoting AML blast survival via kinase signaling. This cytokine activity essentially reduced AML cell susceptibility to specifically engineered CART-123. These findings aligned with established ...

OCI/AML-4, obtained from Dr MD Minden, University Health Network, Toronto, Canada, is a continuous cell line derived from the blast cells of a patient with AML secondary to the treatment of ...

One main goal of anti-cancer therapies is to kill tumor cells without affecting the surrounding normal cells. Therefore, many drugs are designed to target tumor-specific antigens, which are molecules ...