Demi Moore continued her strong awards season run for “The Substance” by taking home the SAG Award for outstanding performance by a female actor in a lead role. The victory was Moore’s third among the major Oscar precursor ceremonies.

Demi Moore delivered a heartfelt speech after winning the award for best actress in a leading role at the SAG Awards.

Demi Moore called her her fellow actors "my greatest teachers" after she won the 2025 SAG Award for outstanding performance by a female actor in a leading role for her performance in 'The Substance' on Sunday,