Antigua Guatemala, commonly known as Antigua or La Antigua, is a city in the central highlands of Guatemala. The city was the capital of the C…Antigua Guatemala, commonly known as Antigua or La Antigua, is a city in the central highlands of Guatemala. The city was the capital of the Captaincy General of Guatemala from 1543 through 1773, with much of its Baroque-influenced architecture and layout dating from that period. These characteristics had it designated as a UNESCO World Heritage Site in 1979. Antigua Guatemala serves as the capital of the homonymous municipality and the Sacatepéquez Department.