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WEBSep 19, 2024 · eLife is a non-profit organisation inspired by research funders and led by scientists. Our mission is to help scientists accelerate discovery by operating a platform for research communication that encourages and recognises the most responsible behaviours in science. eLife Sciences Publications, Ltd is a limited liability non-profit non-stock corporation incorporated in the State of Delaware ...
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WEBeLife is a non-profit organisation inspired by research funders and led by scientists. Our mission is to help scientists accelerate discovery by operating a platform for research communication that encourages and recognises the most responsible behaviours in …
How to measure and evaluate binding affinities | eLife
WEBAug 6, 2020 · Quantitative measurements of biomolecule associations are central to biological understanding and are needed to build and test predictive and mechanistic models. Given the advances in high-throughput technologies and the projected increase in the availability of binding data, we found it especially timely to evaluate the current standards for ...
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WEBSep 17, 2024 · eLife is a non-profit organisation inspired by research funders and led by scientists. Our mission is to help scientists accelerate discovery by operating a platform for research communication that encourages and recognises the most responsible behaviours in science. eLife Sciences Publications, Ltd is a limited liability non-profit non-stock corporation incorporated in the State of Delaware ...
The Natural History of Model Organisms: The secret lives of
WEBJun 4, 2015 · Drosophila: D. hydei (the larger, dark flies) and D. melanogaster and D. simulans (the smaller, lighter flies) interacting at a food source. Although there is little sexual dimorphism between males and females of the D. hydei species, males can be distinguished in the video because they approach other flies to court. In the D. melanogaster and D. simulans species, males are smaller than the ...
Publishing and peer review at eLife · eLife
WEBThe fee for publishing an article with eLife is $2,500, charged at the point we commit to peer reviewing the article. Publication of an eLife Version of Record complies with all major funding agency requirements for immediate online access to the published results of their research grants. An increasing number of funders are also recognising ...
Research Articles - eLife
WEB3 days ago · eLife is a non-profit organisation inspired by research funders and led by scientists. Our mission is to help scientists accelerate discovery by operating a platform for research communication that encourages and recognises the most responsible behaviours in science. eLife Sciences Publications, Ltd is a limited liability non-profit non-stock corporation incorporated in the State of Delaware ...
For Authors: A simpler way to submit to eLife
WEBMar 11, 2019 · eLife is a non-profit organisation inspired by research funders and led by scientists. Our mission is to help scientists accelerate discovery by operating a platform for research communication that encourages and recognises the most responsible behaviours in science. eLife Sciences Publications, Ltd is a limited liability non-profit non-stock corporation incorporated in the State of Delaware ...
A ‘double-edged’ role for type-5 metabotropic glutamate ... - eLife
WEBAug 22, 2024 · We used light-sensitive drugs to identify the brain region-specific role of mGlu5 metabotropic glutamate receptors in the control of pain. Optical activation of systemic JF-NP-26, a caged, normally inactive, negative allosteric modulator (NAM) of mGlu5 receptors, in cingulate, prelimbic, and infralimbic cortices and thalamus inhibited neuropathic pain hypersensitivity.
Sensitive red protein calcium indicators for imaging neural activity
WEBMar 24, 2016 · The new protein indicators detect neural activity with high sensitivity and allow researchers to image previously unseen brain activity. Tests showed that the probes work in cultured neurons and allow imaging of the activity of neurons in mice, flies, fish and worms. History has shown that enhancing the techniques used to study biological ...